NME1 / NM23

NME/NM23 nucleoside diphosphate kinase 1

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.

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Products

ELISA Kits (7)

Type

Custom (2)

Sandwich (5)

Target

NME1 / NM23 (7)

Reactivity

Human (3)

Mouse (1)

Rat (2)

Dog (1)

Format

96-Well Strip Plate (7)

Publications

No (7)

Sample Type

Cell Lysates (1)

Plasma (5)

Serum (5)

Tissue Homogenates (2)

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Mouse NME1 / NM23 (Sandwich ELISA) ELISA Kit - LS-F17248

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human NME1 / NM23 (Sandwich ELISA) ELISA Kit - LS-F33247

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human NME1 / NM23 (Sandwich ELISA) ELISA Kit - LS-F12128

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Dog NME1 / NM23 (Custom ELISA) ELISA Kit - LS-F17247

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Rat NME1 / NM23 (Custom ELISA) ELISA Kit - LS-F17249

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat NME1 / NM23 (Sandwich ELISA) ELISA Kit - LS-F8636

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human NME1 / NM23 (Sandwich ELISA) ELISA Kit - LS-F52313

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

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