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NKP30

natural cytotoxicity triggering receptor 3

Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Gene Name: natural cytotoxicity triggering receptor 3
Synonyms: NCR3, 1C7, CD337 antigen, Activating NK-A1 receptor, Lymphocyte antigen 117, MALS, NKp30, LY117, CD337, NK-p30
Target Sequences: AX367030 AAD18088.1 O14931

Publications (1)

1
Endometrial NK cells are special immature cells that await pregnancy. Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, Gruda R, Hurwitz A, Bdolah Y, Haimov-Kochman R, Yagel S, Mandelboim O. Journal of immunology (Baltimore, Md. : 1950). 2008 181:1869-76. [PubMed:18641324]

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Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
NKP30 (10)
No (10)
6His, C-terminus (2)
Fc, C-terminus (2)
GST (1)
His (1)
His-T7 (2)
Myc-DDK (Flag) (2)
Human (8)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Human Cells (2)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (4)
NKP30 Protein - 12.5% SDS-PAGE of human NCR3 stained with Coomassie Blue
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Wheat Germ Extract
GST
48 kDa
10 µg/$479; 25 µg/$670
NKP30 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
21.4 kDa
20 µg/$150
NKP30 Protein - Recombinant Natural Cytotoxicity Triggering Receptor 3 By SDS-PAGE
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E. coli
His-T7
16.1 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
NKP30 Protein - Recombinant Natural Cytotoxicity Triggering Receptor 3 By SDS-PAGE
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E. coli
His-T7
17.2 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.84kD
10 µg/$297; 50 µg/$468; 500 µg/$1,585; 1 mg/$2,157
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Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.2kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
NKP30 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
NKP30 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.4 kDa
100 µg/$494
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Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.2 kDa
10 µg/$317
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.8 kDa
10 µg/$297
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).