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NFYA

nuclear transcription factor Y, alpha

NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Gene Name: nuclear transcription factor Y, alpha
Synonyms: NFYA, CBF-A, CBF-B, HAP2, HAP2 CCAAT-binding protein, NF-YA
Target Sequences: NM_021705 NP_068351.1 P23511

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Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
NFYA (10)
No (10)
GST (1)
GST, N-terminus (3)
Myc-DDK (Flag) (4)
Human (8)
293T Cells (2)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (4)
NFYA Protein - 12.5% SDS-PAGE of human NFYA stained with Coomassie Blue
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Wheat Germ Extract
GST
63.3 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
33.9kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
E. coli
GST, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
60.58kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
NFYA Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NFYA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.7 kDa
100 µg/$494
NFYA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.7 kDa
20 µg/$150
NFYA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
33.8 kDa
20 µg/$150
NFYA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
33.8 kDa
100 µg/$494
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
33.9 kDa
10 µg/$317; 50 µg/$524
Select
E. coli
GST, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
60.6 kDa
10 µg/$317; 50 µg/$524
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).