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Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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Additional Contact Details
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
NFX1
nuclear transcription factor, X-box binding 1
Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
| Gene Name: | nuclear transcription factor, X-box binding 1 |
| Synonyms: | NFX1, NFX2 |
| Target Sequences: | NM_002504 NP_002495.2 Q12986 |
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