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NFE2L3 is a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
Gene Name: | nuclear factor, erythroid 2-like 3 |
Synonyms: | NFE2L3, NFE2-related factor 3, NF-E2-related factor 3, NRF3 |
Target Sequences: | NM_004289 NP_004280.5 Q9Y4A8 |
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