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NFAT4 / NFATC3 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.
Gene Name: | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
Synonyms: | NFATC3, NF-AT4, NFATX, NF-AT4c, NFAT4, NF-ATc3 |
Target Sequences: | NM_004555 NP_004546.1 Q12968 |
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