NF2 / Merlin

neurofibromin 2 (merlin)

Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.

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Products

Proteins (15)

Type

Over-Expression Lysate (10)

Recombinant (5)

Target

NF2 / Merlin (15)

Publications

No (15)

Tag

6His, N-terminus (1)

GST (1)

His, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (10)

Species

Human (9)

Mouse (1)

Source

293T Cells (5)

E. coli (4)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human NF2 / Merlin Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G137069

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

73.7 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human NF2 / Merlin Protein (Recombinant GST) (Full Length) - LS-G29496

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

34.76 kDa

Price:

2 µg/$439

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Human NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77316

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.5 kDa

Price:

20 µg/$150

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Human NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77319

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

20 µg/$150

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Human NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77318

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

20 µg/$150

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Human NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77320

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

20 µg/$215

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Human NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77322

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.9 kDa

Price:

20 µg/$215

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NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98987

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.5 kDa

Price:

100 µg/$494

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Human NF2 / Merlin Protein (Recombinant His, N-terminus) - LS-G146203

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

69.7kDa

Price:

20 µg/$270; 100 µg/$390

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NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104365

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

100 µg/$494

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NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104366

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

100 µg/$710

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NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104367

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.9 kDa

Price:

100 µg/$710

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NF2 / Merlin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127579

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

100 µg/$494

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Human NF2 / Merlin Protein (Recombinant His-T7) (aa30-239) - LS-G14491

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.6 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Mouse NF2 / Merlin Protein (Recombinant His-T7) (aa30-311) - LS-G14494

Source:

E. coli

Tag:

His-T7

Molecular Weight:

37.3 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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