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Vector Laboratories, Inc.
6737 Mowry Ave
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Neuroserpin
serpin peptidase inhibitor, clade I (neuroserpin), member 1
Neuroserpin is a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
| Gene Name: | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| Synonyms: | SERPINI1, Neuroserpin, Peptidase inhibitor 12, PI12, Serpin I1, PI-12, Protease inhibitor 12 |
| Target Sequences: | NM_005025 NP_005016.1 Q99574 |
Publications (1)
1
Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by a-Synuclein. Leah K Cuddy, Willayat Y Wani, Martino L Morella, Caleb Pitcairn, Kotaro Tsutsumi, Kristina Fredriksen, Craig J Justman, Tom N Grammatopoulos, Nandkishore R Belur, Friederike Zunke, Aarthi Subramanian, Amira Affaneh, Peter T Lansbury Jr, Joseph R Mazzulli. Neuron. 2019 December;104:869-884.e11. [Full Text Article]
[PubMed:31648898]
[PMC:PMC6895429]
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Neuroserpin Mouse anti-Human Monoclonal (1D10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Neuroserpin Rabbit anti-Human Polyclonal (aa19-45) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Neuroserpin Rabbit anti-Human Polyclonal (aa19-45) (Biotin) Antibody
Human
ELISA, Flo, IF, IHC, WB
Biotin Conjugated
200 µl/$952
Neuroserpin Rabbit anti-Human Polyclonal (aa19-45) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Neuroserpin Rabbit anti-Human Polyclonal (aa19-45) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Neuroserpin Rabbit anti-Human Polyclonal (aa19-45) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Neuroserpin Rabbit anti-Human Polyclonal (aa19-45) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Neuroscience
Neuroserpin Goat anti-Human Polyclonal (aa399-410) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Pig, Horse, Human, Monkey
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
Neuroserpin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$412
Neuroserpin Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC-P, IP, WB
Unconjugated
100 µl/$412
Sandwich
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$730
Neuroserpin Rabbit anti-Mouse Polyclonal (aa181-410) Antibody
Mouse, Rat
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
Neuroserpin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Neuroserpin Rabbit anti-Mouse Polyclonal Antibody
Mouse
IHC, IHC-P
Unconjugated
100 µl/$412
Neuroserpin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
Neuroserpin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
Neuroserpin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Neuroserpin Rat anti-Human Monoclonal (aa19-410) Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$872
Neuroserpin Sheep anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µl/$438; 1 ml/$589; 10 ml/$3,317
Neuroserpin Sheep anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$449; 1 mg/$614; 10 mg/$3,317
Neuroserpin Sheep anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
100 µg/$409; 1 mg/$541; 10 mg/$3,523
Neuroserpin Sheep anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
100 µg/$483; 1 mg/$700; 10 mg/$3,568
Neuroserpin Sheep anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
100 µg/$483; 1 mg/$700; 10 mg/$3,568
Neuroserpin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Neuroserpin Mouse anti-Human Monoclonal (Preservative Free) (08) Antibody
Human
ELISA, IHC-P
Unconjugated, Preservative Free
100 µl/$412
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