NELFA / WHSC2

negative elongation factor complex member A

NELFA / WHSC2 is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

NELFA / WHSC2 (5)

Publications

No (5)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human NELFA / WHSC2 Protein (Recombinant His) - LS-G1079

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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NELFA / WHSC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115816

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.1 kDa

Price:

100 µg/$494

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Human NELFA / WHSC2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71283

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.1 kDa

Price:

20 µg/$1,107

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Human NELFA / WHSC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89405

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.1 kDa

Price:

20 µg/$150

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Human NELFA / WHSC2 Protein (Recombinant GST) (Full Length) - LS-G30899

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83.7 kDa

Price:

10 µg/$479; 25 µg/$670

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