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Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.
Gene Name: | NIMA-related kinase 3 |
Family/Subfamily: | Protein Kinase , NEK |
Synonyms: | NEK3, HSPK 36, HSPK36, NIMA-related kinase 3, NimA-related protein kinase 3, Hydroxyalkyl-protein kinase, Phosphorylase B kinase kinase, Glycogen synthase A kinase |
Target Sequences: | AB072828 CAD34740.1 P51956 |
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