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NEDD8

neural precursor cell expressed, developmentally down-regulated 8

Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

Gene Name: neural precursor cell expressed, developmentally down-regulated 8
Synonyms: NEDD8, NEDD-8, Neddylin, Ubiquitin-like protein Nedd8
Target Sequences: NM_006156 NP_006147.1 Q15843

☰ Filters
Antibodies (38)
Proteins (8)
ELISA Kits (1)
Cell-Based (1)
Primary (38)
Recombinant (8)
NEDD8 (47)
Human (37)
Mouse (18)
Rat (16)
Bovine (2)
Dog (1)
Monkey (3)
Rabbit (1)
Xenopus (1)
Yeast (1)
IHC (24)
IHC-Fr (1)
IHC-P (11)
WB (37)
Flo (4)
ELISA (19)
ICC (1)
IF (6)
IP (3)
Peptide-ELISA (2)
rabbit (33)
mouse (4)
sheep (1)
Product Group
IHCPlus (3)
IgG (27)
IgG1 (3)
IgG2b (1)
monoclonal mc (4)
polyclonal pc (34)
1A7 (2)
5B8 (1)
96-Well Microplate (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (28)
aa1-32 (7)
N-Terminus (4)
aa1-81 (2)
10-90 aa, N-terminal (1)
Asp21 (1)
aa10-59 (1)
aa2-77 (1)
No (46)
Yes (1)
Adherent Cell Cultures (1)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (2)
His (1)
His, N-Terminal (1)
Human (8)
E. coli (6)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (4)
NEDD8 Antibody - Anti-NEDD8 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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NEDD8 Rabbit anti-Human Polyclonal (aa10-59) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
NEDD8 Antibody - Anti-NEDD8 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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NEDD8 Mouse anti-Human Monoclonal (5B8) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
NEDD8 Antibody - IHC of paraffin-embedded cervical cancer tissues using NEDD8 mouse monoclonal antibody with DAB staining.
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NEDD8 Mouse anti-Human Monoclonal (1A7) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
NEDD8 Antibody - NEDD8 Antibody in Immunohistochemistry (IHC)
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NEDD8 Mouse anti-Human Monoclonal (1A7) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
NEDD8 Antibody - IHC of paraffin-embedded human colon carcinoma
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NEDD8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Xenopus, Rat, Mouse, Bovine, Human, Monkey
Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$688
NEDD8 Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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NEDD8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NEDD8 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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NEDD8 Rabbit anti-Human Polyclonal (aa1-81) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
NEDD8 Antibody - Immunohistochemistry of paraffin-embedded human esophagus using NEDD8 antibodyat dilution of 1:100 (40x lens).
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NEDD8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
NEDD8 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
Select
NEDD8 Sheep anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
500 µg/$393
NEDD8 Antibody - Immunohistochemical analysis of NEDD8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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NEDD8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
NEDD8 Antibody - NEDD8 was detected in paraffin-embedded sections of human lung cancer tissues using rabbit anti- NEDD8 Antigen Affinity purified polyclonal antibody
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NEDD8 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
NEDD8 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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NEDD8 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
60 µl/$460
Select
NEDD8 Rabbit anti-Human Polyclonal (aa1-32) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
NEDD8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
NEDD8 Antibody - Western blot of Neddylin antibody
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NEDD8 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NEDD8 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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NEDD8 Rabbit anti-Human Polyclonal (aa1-32) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
NEDD8 Antibody - IHC of NEDD8 (D21) pAb in paraffin-embedded human lung carcinoma tissue.
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NEDD8 Rabbit anti-Human Polyclonal (Asp21) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
NEDD8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
NEDD8 Antibody - Western blot of Jurkat cell lysate using NEDD8 Antibody
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NEDD8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
Viewing 1-25 of 47 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).