NECAB3

N-terminal EF-hand calcium binding protein 3

NECAB3 interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

NECAB3 (6)

Publications

No (6)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human NECAB3 Protein (Recombinant GST) (Full Length) - LS-G34908

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NECAB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82925

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.6 kDa

Price:

20 µg/$150

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Human NECAB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82926

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.2 kDa

Price:

20 µg/$150

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Human NECAB3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68723

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.6 kDa

Price:

20 µg/$1,107

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NECAB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109290

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.2 kDa

Price:

100 µg/$494

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NECAB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109291

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.6 kDa

Price:

100 µg/$494

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