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NECAB3

N-terminal EF-hand calcium binding protein 3

NECAB3 interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: N-terminal EF-hand calcium binding protein 3
Synonyms: NECAB3, APBA2BP, DJ63M2.5, DJ63M2.4, EFCBP3, STIP3, XB51, Nek2-interacting protein 1, NIP1, X11L-binding protein 51
Target Sequences: AB039947 BAB16413.1 Q96P71

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Products
Antibodies (16)
Primary (16)
NECAB3 (16)
Human (16)
Mouse (10)
Rat (5)
Bovine (1)
Chimpanzee (3)
Drosophila (3)
Gibbon (3)
IHC (4)
IHC-P (2)
WB (16)
ELISA (3)
ICC (1)
IF (6)
IP (1)
Peptide-ELISA (2)
rabbit (16)
Product Group
IHCPlus (1)
IgG (6)
polyclonal pc (16)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (10)
N-Terminus (4)
aa179-228 (4)
290-370 aa, C-terminal (1)
C-Terminus (1)
aa321-370 (1)
No (16)
NECAB3 Antibody - Anti-NECAB3 / NIP1 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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NECAB3 Rabbit anti-Human Polyclonal (aa321-370) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
NECAB3 Antibody - Immunohistochemical analysis of NIP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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NECAB3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
NECAB3 Antibody - Western blot of APBA2BP antibody
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NECAB3 Rabbit anti-Human Polyclonal (290-370 aa, C-terminal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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NECAB3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
NECAB3 Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using NECAB3 antibody.
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NECAB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
NECAB3 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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NECAB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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NECAB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
100 µl/$386
NECAB3 Antibody - NECAB3 / NIP1 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NECAB3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
NECAB3 Antibody - NECAB3 / NIP1 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NECAB3 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Drosophila, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
NECAB3 Antibody - NECAB3 / NIP1 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NECAB3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Drosophila, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
NECAB3 Antibody - NECAB3 / NIP1 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NECAB3 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Drosophila, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
NECAB3 Antibody - NECAB3 / NIP1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NECAB3 Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human
WB
Unconjugated
100 µl/$424
NECAB3 Antibody - NECAB3 / NIP1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NECAB3 Rabbit anti-Human Polyclonal (aa179-228) (HRP) Antibody
Mouse, Rat, Gibbon, Human
WB
HRP Conjugated
100 µl/$469
NECAB3 Antibody - NECAB3 / NIP1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NECAB3 Rabbit anti-Human Polyclonal (aa179-228) (Biotin) Antibody
Mouse, Rat, Gibbon, Human
WB
Biotin Conjugated
100 µl/$469
NECAB3 Antibody - NECAB3 / NIP1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NECAB3 Rabbit anti-Human Polyclonal (aa179-228) (FITC) Antibody
Mouse, Rat, Gibbon, Human
WB
FITC Conjugated
100 µl/$469
NECAB3 Antibody - Western blot analysis of extracts of various cell lines, using NECAB3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
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NECAB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-16 of 16 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).