NDP

Norrie disease (pseudoglioma)

Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.

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Products

ELISA Kits (5)

Type

Custom (1)

Sandwich (4)

Target

NDP (5)

Reactivity

Human (3)

Mouse (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

Publications

No (5)

Sample Type

Cell Culture Supernatants (1)

Plasma (4)

Serum (4)

Tissue Homogenates (1)

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Human NDP (Sandwich ELISA) ELISA Kit - LS-F49997

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.41 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$635

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Mouse NDP (Sandwich ELISA) ELISA Kit - LS-F17469

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human NDP (Sandwich ELISA) ELISA Kit - LS-F12129

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Human NDP (Sandwich ELISA) ELISA Kit - LS-F33241

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Bovine NDP (Custom ELISA) ELISA Kit - LS-F17470

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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