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NDN / Necdin

necdin, melanoma antigen (MAGE) family member

Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences.

Gene Name: necdin, melanoma antigen (MAGE) family member
Synonyms: NDN, Necdin, Necdin homolog (mouse), HsT16328, Necdin (mouse) homolog, PWCR
Target Sequences: NM_002487 NP_002478.1 Q99608

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Products
Antibodies (24)
Primary (24)
NDN / Necdin (24)
Human (24)
Mouse (1)
Rat (1)
Bovine (3)
Chimpanzee (3)
Dog (3)
Goat (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
Sheep (3)
IHC (4)
IHC-P (3)
WB (20)
Flo (7)
ELISA (8)
IF (4)
Peptide-ELISA (1)
rabbit (17)
mouse (7)
Product Group
IHCPlus (1)
IgG (11)
IgG1 (4)
IgG2a (2)
IgG2a,k (1)
monoclonal mc (7)
polyclonal pc (17)
1B3 (1)
OTI1B1 (2)
OTI3A12 (2)
OTI5D1 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
Carrier-free (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (13)
aa43-71 (7)
aa179-228 (4)
aa75-109 (1)
No (24)
NDN / Necdin Antibody - Anti-NDN / Necdin antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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NDN / Necdin Mouse anti-Human Monoclonal (1B3) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
NDN / Necdin Antibody - IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-NDN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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NDN / Necdin Mouse anti-Human Monoclonal (OTI5D1) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
NDN / Necdin Antibody - IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-NDN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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NDN / Necdin Mouse anti-Human Monoclonal (Carrier-free) (OTI5D1) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NDN / Necdin Antibody - Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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NDN / Necdin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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NDN / Necdin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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NDN / Necdin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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NDN / Necdin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
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NDN / Necdin Rabbit anti-Human Polyclonal (aa43-71) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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NDN / Necdin Rabbit anti-Human Polyclonal (aa43-71) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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NDN / Necdin Rabbit anti-Human Polyclonal (aa43-71) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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NDN / Necdin Rabbit anti-Human Polyclonal (aa43-71) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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NDN / Necdin Rabbit anti-Human Polyclonal (aa43-71) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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NDN / Necdin Rabbit anti-Human Polyclonal (aa43-71) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
NDN / Necdin Antibody - NDN Antibody western blot of Ramos cell line lysates (35 ug/lane). The NDN antibody detected the NDN protein (arrow).
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NDN / Necdin Rabbit anti-Human Polyclonal (aa43-71) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
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NDN / Necdin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NDN / Necdin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NDN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NDN.
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NDN / Necdin Mouse anti-Human Monoclonal (OTI1B1) Antibody
Human
WB
Unconjugated
100 µl/$434
NDN / Necdin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NDN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NDN.
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NDN / Necdin Mouse anti-Human Monoclonal (Carrier-free) (OTI1B1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
NDN / Necdin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NDN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NDN.
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NDN / Necdin Mouse anti-Human Monoclonal (OTI3A12) Antibody
Human
WB
Unconjugated
100 µl/$434
NDN / Necdin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NDN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NDN.
Select
NDN / Necdin Mouse anti-Human Monoclonal (Carrier-free) (OTI3A12) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
NDN / Necdin Antibody - NDN / Necdin antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NDN / Necdin Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human
WB
Unconjugated
100 µl/$424
NDN / Necdin Antibody - NDN / Necdin antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NDN / Necdin Rabbit anti-Human Polyclonal (aa179-228) (HRP) Antibody
Rabbit, Goat, Dog, Sheep, Bovine, Pig, Horse, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
NDN / Necdin Antibody - NDN / Necdin antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NDN / Necdin Rabbit anti-Human Polyclonal (aa179-228) (Biotin) Antibody
Rabbit, Goat, Dog, Sheep, Bovine, Pig, Horse, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
NDN / Necdin Antibody - NDN / Necdin antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NDN / Necdin Rabbit anti-Human Polyclonal (aa179-228) (FITC) Antibody
Rabbit, Goat, Dog, Sheep, Bovine, Pig, Horse, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
NDN / Necdin Antibody - Western blot of lysate from human heart tissue lysate with NDN Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.
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NDN / Necdin Rabbit anti-Human Polyclonal (aa75-109) Antibody
Human
WB
Unconjugated
400 µl/$393
Viewing 1-24 of 24 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).