NDE1

nudE neurodevelopment protein 1

Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

NDE1 (8)

Publications

No (8)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human NDE1 Protein (Recombinant His) - LS-G1249

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human NDE1 Protein (Recombinant GST) (Full Length) - LS-G34060

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.59 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NDE1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71061

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

20 µg/$1,107

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Human NDE1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71062

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

20 µg/$1,107

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NDE1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101490

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

100 µg/$494

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Human NDE1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88659

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

20 µg/$150

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Human NDE1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88660

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

20 µg/$150

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NDE1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126274

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

100 µg/$494

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