NCSTN / Nicastrin

nicastrin

NCSTN / Nicastrin is a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

☰ Filters

Products

Antibodies (40)

Proteins (11)

ELISA Kits (1)

Type

Custom (1)

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (2)

Primary (40)

Recombinant (8)

Target

NCSTN / Nicastrin (52)

Reactivity

Human (31)

Mouse (10)

Rat (17)

Bat (1)

Bovine (1)

Horse (1)

Pig (1)

Application

IHC (8)

IHC-P (3)

WB (31)

Flo (3)

ELISA (11)

ICC (1)

IF (5)

IP (3)

Peptide-ELISA (2)

Host

rabbit (40)

Product Group

IHCPlus (2)

Isotype

IgG (12)

Clonality

polyclonal pc (40)

Format

96-Well Microplate (1)

APC (2)

APC Conjugated (2)

Biotin Conjugated (2)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (2)

PE Conjugated (3)

Preservative Free (1)

Unconjugated (24)

more less

Epitope

aa35-534 (8)

aa420-655 (8)

C-Terminus (1)

aa659-709 (1)

aa72-88 (1)

aa99-133 (1)

Publications

No (52)

Tag

Fc (1)

GST (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

His,C-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (4)

Human Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Supernatant (1)

Low Endotoxin Level

Low endotoxin level (3)

Select

IHC-plus™ NCSTN / Nicastrin Antibody LS-B1380

(4.0) Rating

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ NCSTN / Nicastrin Antibody LS-B530

(4.0) Rating

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

Select

NCSTN / Nicastrin Antibody (PE) LS-C488465

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

Flo

Format:

PE Conjugated

Price:

25 Tests/$293; 100 Tests/$376

Select

NCSTN / Nicastrin Antibody LS-C806059

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

NCSTN / Nicastrin Antibody LS-C401888

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

NCSTN / Nicastrin Antibody LS-C488469

Antibody:

NCSTN / Nicastrin Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

NCSTN / Nicastrin Antibody LS-C660342

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

NCSTN / Nicastrin Antibody LS-C488463

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

Select

NCSTN / Nicastrin Antibody (Preservative Free) LS-C818590

Antibody:

NCSTN / Nicastrin Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody

Reactivity:

Mouse

Applications:

ELISA, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

NCSTN / Nicastrin Antibody LS-C192373

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

NCSTN / Nicastrin Antibody LS-C405202

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

NCSTN / Nicastrin Antibody (C-Terminus) LS-C25766

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$688

Select

NCSTN / Nicastrin Antibody LS-C488472

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

NCSTN / Nicastrin Antibody LS-C833948

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

NCSTN / Nicastrin Antibody LS-C488466

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

NCSTN / Nicastrin Antibody (aa659-709) LS-C761984

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal (aa659-709) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

NCSTN / Nicastrin Antibody (aa99-133) LS-C392706

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal (aa99-133) Antibody

Reactivity:

Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

NCSTN / Nicastrin Antibody LS-C488468

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Flo

Format:

Unconjugated

Price:

100 µl/$412

Select

NCSTN / Nicastrin Antibody LS-C488471

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

NCSTN / Nicastrin Antibody LS-C488470

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$375; 200 µl/$473; 400 µl/$648

Select

NCSTN / Nicastrin Antibody (aa420-655) LS-C295627

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal (aa420-655) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

NCSTN / Nicastrin Antibody (aa72-88) LS-C313344

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal (aa72-88) Antibody

Reactivity:

Rat, Pig, Horse, Bat, Bovine, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

NCSTN / Nicastrin Antibody LS-C749506

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

NCSTN / Nicastrin Antibody LS-C335080

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

NCSTN / Nicastrin Antibody (FITC) LS-C488464

Antibody:

NCSTN / Nicastrin Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

25 Tests/$278; 100 Tests/$346

Viewing 1-25 of 52 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.