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NCKAP1L encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.
Gene Name: | NCK-associated protein 1-like |
Synonyms: | NCKAP1L, HEM1, Hematopoietic protein 1, NCK-associated protein 1-like |
Target Sequences: | NM_005337 NP_005328.2 P55160 |
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