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NCF1 / p47phox / p47 phox

neutrophil cytosolic factor 1

NCF1 encodes neutrophil cytosolic factor 1, the 47-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF1, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.

Gene Name: neutrophil cytosolic factor 1
Synonyms: NCF1, NCF1A, Neutrophil cytosolic factor 1, NCF-47K, Nox organizer 2, NOXO2, p47-phox, p47phox, SH3PXD1A, NADPH oxidase organizer 2, NCF-1, Neutrophil cytosol factor 1, Nox-organizing protein 2
Target Sequences: NM_000265 NP_000256.4 P14598

Publications (2)

1
NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury. Fischer MT, Sharma R, Lim JL, Haider L, Frischer JM, Drexhage J, Mahad D, Bradl M, van Horssen J, Lassmann H. Brain : a journal of neurology. 2012 135:886-99. (IHC-P; Human) [Full Text Article] [PubMed:22366799] [PMC:PMC3286337] Related Antibodies: LS-B2365.
2
Characterization of the inflammatory response to solid cancer metastases in the human brain. Berghoff AS, Lassmann H, Preusser M, H[Character f6]ftberger R. Clinical & experimental metastasis. 2013 Jan;30:69-81. [Full Text Article] [PubMed:22752508] Related Antibodies: LS-B2365.

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NCF1 / p47phox / p47 phox (4)
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NCF1 / p47phox / p47 phox ELISA Kit
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Cell-Based
96-Well Microplate
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Colorimetric - 450nm (TMB)
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1 Plate/$534
NCF1 / p47phox / p47 phox ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
NCF1 / p47phox / p47 phox ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
NCF1 / p47phox / p47 phox ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).