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NAT1 / AAC1 is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
Synonyms: | NAT1, AAC1, Arylamide acetylase 1, MNAT, N-acetyltransferase type 1, NATI, NAT-1 |
Target Sequences: | NM_000662 NP_000653.3 P18440 |
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