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Voltage-independent, cation-nonselective channel which is permeable to sodium, potassium and calcium ions. Responsible for the background sodium ion leak current in neurons and controls neuronal excitability. Activated either by neuropeptides substance P or neurotensin. Required for normal respiratory rhythm and neonatal survival.
Gene Name: | sodium leak channel, non-selective |
Family/Subfamily: | Ion channel , Calcium channel - other |
Synonyms: | NALCN, BA430M15.1, CanIon, VGCNL1, Voltage gated channel like 1 |
Target Sequences: | AX319778 AAN10255.1 Q8IZF0 |
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