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6737 Mowry Ave
Newark, CA 94560
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N6AMT1
N-6 adenine-specific DNA methyltransferase 1 (putative)
Heterodimeric methyltransferase that catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid.
| Gene Name: | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| Synonyms: | N6AMT1, M.HsaHemK2P, HEMK2, N6AMT, C21orf127, MTQ2, N6-DNA-methyltransferase, PRED28 |
| Target Sequences: | NM_013240 NP_037372.4 Q9Y5N5 |
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