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N-CoR / NCOR1

nuclear receptor corepressor 1

N-CoR / NCOR1 is a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Gene Name: nuclear receptor corepressor 1
Synonyms: NCOR1, HCIT529I10, KIAA1047, N-CoR1, TRAC1, HN-CoR, N-CoR, Nuclear co-repressor n-cor, Nuclear receptor corepressor 1
Target Sequences: NM_006311 NP_006302.2 O75376

Publications (1)

1
The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells. Beatrice Pflüger-Müller, James A Oo, Jan Heering, Timothy Warwick, Ewgenij Proschak, Stefan Günther, Mario Looso, Flávia Rezende, Christian Fork, Gerd Geisslinger, Dominique Thomas, Robert Gurke, Dieter Steinhilber, Marcel Schulz, Matthias S Leisegang, Ralf P Brandes. Basic research in cardiology. 2020 April;115:34. [PubMed:32323032] [PMC:PMC7176595] Related Antibodies: LS-C108878.

☰ Filters
Antibodies (40)
ELISA Kits (9)
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Custom (2)
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Primary (40)
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N-CoR / NCOR1 (52)
Human (45)
Mouse (27)
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rabbit (36)
mouse (3)
sheep (1)
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monoclonal mc (3)
polyclonal pc (37)
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96-Well Strip Plate (7)
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aa1510-1540 (1)
aa1525-1575 (1)
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Human (2)
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N-CoR / NCOR1 Antibody - IHC of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right), showing nuclear location with DAB staining using NCOR1 mouse monoclonal antibody.
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N-CoR / NCOR1 Mouse anti-Human Monoclonal (7A7A9) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$467
N-CoR / NCOR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
39 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
N-CoR / NCOR1 Antibody - Detection of Mouse NCOR by Western Blot. Samples: Whole cell lysate (50 ug) from TCMK-1, Renca, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-NCOR antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa1525-1575) Antibody
Mouse, Human
ChIP-Seq, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
N-CoR / NCOR1 Antibody - Anti-NCOR1 / N-CoR antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa484-533) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
N-CoR / NCOR1 Antibody - Anti-NCOR1 / N-CoR antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa484-533) (HRP) Antibody
Mouse, Bovine, Bat, Gibbon, Human, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
N-CoR / NCOR1 Antibody - Anti-NCOR1 / N-CoR antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa484-533) (Biotin) Antibody
Mouse, Bovine, Bat, Gibbon, Human, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
N-CoR / NCOR1 Antibody - Anti-NCOR1 / N-CoR antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa484-533) (FITC) Antibody
Mouse, Bovine, Bat, Gibbon, Human, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
N-CoR / NCOR1 Antibody - Immunohistochemical analysis of NCOR1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
N-CoR / NCOR1 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa16-47) Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
400 µl/$393
N-CoR / NCOR1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa2000-2050) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
N-CoR / NCOR1 Antibody - 1:100 staining human colon tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
N-CoR / NCOR1 Antibody - IHC of NCoR1 (H76) pAb in paraffin-embedded human breast carcinoma tissue.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (His76) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
N-CoR / NCOR1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
N-CoR / NCOR1 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using NCoR1 Antibody. The picture on the right is blocked with the synthesized peptide.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa51-100) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
N-CoR / NCOR1 Antibody - Immunofluorescence analysis of U20S cells.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
N-CoR / NCOR1 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right), showing nuclear location with DAB staining using N-CoR Monoclonal Antibody.
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N-CoR / NCOR1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa16-47) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa16-47) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa16-47) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa16-47) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal (aa16-47) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
N-CoR / NCOR1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using NCoR1 antibody.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
N-CoR / NCOR1 Antibody - Immunofluorescence staining of NCOR1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human NCOR1 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus and cytoplasm.
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N-CoR / NCOR1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
Viewing 1-25 of 52 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).