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MYOD / MYOD1

myogenic differentiation 1

Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.

Gene Name: myogenic differentiation 1
Synonyms: MYOD1, BHLHc1, Myogenic differentiation 1, Myf-3, MYOD, Myogenic factor 3, PUM, MYF3
Target Sequences: NM_002478 NP_002469.2 P15172

Publications (2)

1
Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus. Sempou E, Lakhani OA, Amalraj S, Khokha MK. Frontiers in physiology. 2018 December;9:1705. [Full Text Article] [PubMed:30564136] [PMC:PMC6288790] Related Antibodies: LS-C143580.
2
Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression. Agnes Badu-Mensah, Xiufang Guo, Christopher W McAleer, John W Rumsey, James J Hickman. Scientific reports. 2020 August;10:14302. [Full Text Article] [PubMed:32868812] [PMC:PMC7459299] Related Antibodies: LS-C263888.

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
MYOD / MYOD1 (4)
No (4)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
MYOD / MYOD1 Protein - 12.5% SDS-PAGE of human MYOD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
60.9 kDa
2 µg/$439
MYOD / MYOD1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MYOD / MYOD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.3 kDa
20 µg/$150
MYOD / MYOD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.3 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).