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Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Gene Name: | myosin, light chain 2, regulatory, cardiac, slow |
Synonyms: | MYL2, MLC2, Myosin light chain 2, MLC-2, RLC of myosin, CMH10, MLC-2v |
Target Sequences: | NM_000432 NP_000423.2 P10916 |
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