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MYB / c-Myb

v-myb avian myeloblastosis viral oncogene homolog

MYB / c-Myb is a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.

Gene Name: v-myb avian myeloblastosis viral oncogene homolog
Synonyms: MYB, C-myb_CDS, C-myb8B_CDS, C-myb protein (140 AA), C-myb10A_CDS, C-myb13A_CDS, Efg, Transcriptional activator Myb, C-myb, C-myb14A_CDS, Cmyb, Proto-oncogene c-Myb
Target Sequences: NM_005375 NP_005366.2 P10242

Publications (4)

1
Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome. Hussein K, Theophile K, Bsche G, Schlegelberger B, Ghring G, Kreipe H, Bock O. Leukemia research. 2010 34:328-34. (IHC) [PubMed:19615744]
2
The Expression of c-Myb Correlates with the Levels of Rhabdomyosarcoma-specific Marker Myogenin. Kaspar P, Zikova M, Bartunek P, Sterba J, Strnad H, Kren L, Sedlacek R. Scientific reports. 2015 5:15090. (IHC; Mouse) [Full Text Article] [PubMed:26462877] [PMC:PMC4604482] Related Antibodies: LS-B5315.
3
Aberrant expression of AID and AID activators of NF-?B and PAX5 is irrelevant to EBV-associated gastric cancers, but is associated with carcinogenesis in certain EBV-non-associated gastric cancers. Mohri T, Nagata K, Kuwamoto S, Matsushita M, Sugihara H, Kato M, Horie Y, Murakami I, Hayashi K. Oncology letters. 2017 13:4133-4140. (ICC; Human) [Full Text Article] [PubMed:28588701] [PMC:PMC5452920]
4
Higher Expression of Activation-induced Cytidine Deaminase Is Significantly Associated with Merkel Cell Polyomavirus-negative Merkel Cell Carcinomas. Matsushita M, Iwasaki T, Nonaka D, Kuwamoto S, Nagata K, Kato M, Kitamura Y, Hayashi K. Yonago acta medica. 2017 September;60:145-153. [Full Text Article] [PubMed:28959124] [PMC:PMC5611468]
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ELISA Kits (8)
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MYB / c-Myb ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
MYB / c-Myb ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$579
MYB / c-Myb ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
MYB / c-Myb ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
MYB / c-Myb ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
MYB / c-Myb ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
MYB / c-Myb ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
MYB / c-Myb ELISA Kit
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DNA Binding Phosphorylation
12 x 8-Well Microstrips
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$735
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).