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MX2
Myxovirus (influenza) Resistance 2, Homolog Of Murine (MX2)
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.
| Gene Name: | Myxovirus (influenza) Resistance 2, Homolog Of Murine (MX2) |
| Synonyms: | MX2, MXB, MX dynamin-like GTPase 2, interferon-induced GTP-binding protein Mx2, myxovirus resistance protein 2, interferon-regulated resistance GTP-binding protein MXB |
| Target Sequences: | NM_002463 NP_002454.1 P20592 |
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