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MX1 / MX

Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Gene Name: Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
Synonyms: MX1, Interferon-induced protein p78, Myxovirus resistance protein 1, IFI-78K, IFI78, MX, MxA, Myxoma resistance protein 1
Target Sequences: NM_002462 NP_002453.2 P20591

Publications (1)

1
IgE-Mediated Immune Response and Antibody-Mediated Rejection. Federica Rascio, Paola Pontrelli, Giuseppe Stefano Netti, Elisabetta Manno, Barbara Infante, Simona Simone, Giuseppe Castellano, Elena Ranieri, Michela Seveso, Emanuele Cozzi, Loreto Gesualdo, Giovanni Stallone, Giuseppe Grandaliano. Clinical journal of the American Society of Nephrology : CJASN. 2020 Oct;15:1474-1483. [Full Text Article] [PubMed:32907809] [PMC:PMC7536744]

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ELISA Kits (6)
Development Kit (2)
Sandwich (4)
MX1 / MX (6)
Human (3)
Rat (2)
Monkey (1)
Product Group
DevKit DuoPlus (2)
96-Well Strip Plate (4)
Antibody Pair and Standard (2)
No (5)
Yes (1)
Cell Culture Supernatants (4)
Cell Lysates (4)
Plasma (2)
Serum (2)
Tissue Homogenates (5)
MX1 / MX ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
MX1 / MX ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$792
MX1 / MX ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
MX1 / MX ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,386; 1000 Wells/$2,087
MX1 / MX ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,370; 1000 Wells/$2,059
MX1 / MX ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$848
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).