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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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MUC5B
mucin 5B, oligomeric mucus/gel-forming
MUC5B is a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.
Vagal sensory neurons drive mucous cell metaplasia. Sébastien Talbot, Benjamin Doyle, Junwei Huang, Jo-Chiao Wang, Maryam Ahmadi, David P Roberson, Ajay Yekkirala, Simmie L Foster, Liam E Browne, Bruce P Bean, Bruce D Levy, Clifford J Woolf. The Journal of allergy and clinical immunology. 2020 June;145:1693-1696.e4. [Full Text Article]
[PubMed:31954778]
2
Combined Expression of Plasma Thrombospondin-2 and CA19-9 for Diagnosis of Pancreatic Cancer and Distal Cholangiocarcinoma: A Proteome Approach. Tessa Y S Le Large , Laura L Meijer , Rosita Paleckyte, Lenka N C Boyd, Bart Kok, Thomas Wurdinger, Tim Schelfhorst, Sander R Piersma, Thang V Pham, Nicole C T van Grieken, Barbara M Zonderhuis, Freek Daams, Hanneke W M van Laarhoven, Maarten F Bijlsma, Connie R Jimenez, Elisa Giovannetti , Geert Kazemier. The oncologist. 2020 Apr;25:e634-e643. [Full Text Article]
[PubMed:31943574]
[PMC:PMC7160420]
3
Quantification of very late xerostomia in head and neck cancer patients after irradiation. Grace C Blitzer, Nicole M Rogus-Pulia, Cristina Paz, Kwangok P Nickel, Vanessa L Cannaday, Cynthia A Kelm-Nelson, Sailendharan Sudakaran, Richard J Chappell, Tiffany Glazer, Randall J Kimple. Laryngoscope investigative otolaryngology. 2022 August;7:1018-1024. [Full Text Article]
[PubMed:36000048]
[PMC:PMC9392383]
4
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways. Yan Shin J Liao, Shin Ping Kuan, Maria V Guevara, Emily N Collins, Kalina R Atanasova, Joshua S Dadural, Kevin Vogt, Veronica Schurmann, Laura Bravo, Eda Eken, Mariana Sponchiado, Leah R Reznikov. American journal of physiology. Lung cellular and molecular physiology. 2020 May;318:L873-L887. [Full Text Article]
[PubMed:32160007]
[PMC:PMC7272746]
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PLEASE NOTE
For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.
The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).