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MTO1 is a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | mitochondrial tRNA translation optimization 1 |
Synonyms: | MTO1, COXPD10, CGI-02, Homolog of yeast Mto1, Mitochondrial MTO1-3 |
Target Sequences: | NM_012123 NP_036255.2 Q9Y2Z2 |
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