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MTNR1A / Melatonin Receptor 1a
melatonin receptor 1A
MTNR1A / Melatonin Receptor 1a is one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
| Gene Name: | melatonin receptor 1A |
| Family/Subfamily: | GPCR , Melatonin |
| Synonyms: | MTNR1A, Mel-1a melatonin receptor, MEL-1A-R, Melatonin 1a receptor, Melatonin receptor 1A, MT1 melatonin receptor, MT1 receptor, Mel1a receptor, Melatonin receptor type 1A, MT1 |
| Target Sequences: | NM_005958 NP_005949.1 P48039 |
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