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MTNR1A / Melatonin Receptor 1a

melatonin receptor 1A

MTNR1A / Melatonin Receptor 1a is one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Gene Name: melatonin receptor 1A
Family/Subfamily: GPCR , Melatonin
Synonyms: MTNR1A, Mel-1a melatonin receptor, MEL-1A-R, Melatonin 1a receptor, Melatonin receptor 1A, MT1 melatonin receptor, MT1 receptor, Mel1a receptor, Melatonin receptor type 1A, MT1
Target Sequences: NM_005958 NP_005949.1 P48039

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Products
Antibodies (65)
Primary (65)
MTNR1A / Melatonin Receptor 1a (65)
Human (33)
Mouse (17)
Rat (9)
Bovine (19)
Cow (16)
Goat (8)
Monkey (4)
Sheep (3)
IHC (5)
IHC-P (3)
WB (60)
ELISA (5)
ICC (9)
IF (4)
IP (8)
Peptide-ELISA (2)
rabbit (48)
mouse (16)
goat (1)
Product Group
GPCR Database Antibodies (2)
PathPlus Neuro (2)
IgG (15)
IgG2a,k (8)
monoclonal mc (16)
polyclonal pc (49)
APC (6)
APC Conjugated (6)
Biotin Conjugated (7)
Cy3 Conjugated (6)
Cy7 Conjugated (6)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (6)
Unconjugated (20)
aa216-257 (16)
aa296-350 (8)
aa300-353 (8)
aa312-366 (8)
C-Terminus (4)
Cytoplasmic Domain (2)
160-240 aa, Internal (1)
Internal (1)
aa132-144 (1)
aa191-240 (1)
aa80-172 (1)
No (64)
Yes (1)
MTNR1A / Melatonin Receptor 1a Antibody - Anti-MTNR1A antibody IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
MTNR1A / Melatonin Receptor 1a Antibody - Anti-MTNR1A / Melatonin Receptor 1a antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
MTNR1A / Melatonin Receptor 1a Antibody - MTR-1A staining in rat brain. Paraffin-embedded rat brain is stained with MTR-1A Antibody used at 1:1000 dilution.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
0.1 mg/$432
MTNR1A / Melatonin Receptor 1a Antibody - Western Blot; Sample: Recombinant MTNR1A, Mouse.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Mouse Polyclonal (aa300-353) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
MTNR1A / Melatonin Receptor 1a Antibody
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal (aa296-350) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
MTNR1A / Melatonin Receptor 1a Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using MTNR1A Polyclonal Antibody at dilution of 1:100.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal (aa80-172) Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$450
MTNR1A / Melatonin Receptor 1a Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using MTNR1A Polyclonal Antibody at dilution of 1:40.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MTNR1A / Melatonin Receptor 1a Antibody - Peptide - + Immunofluorescence analysis of HepG2 cells, using MTR1A antibody.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
100 µg/$357
MTNR1A / Melatonin Receptor 1a Antibody - Western blot analysis of extracts of various cell lines, using MTNR1A antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
MTNR1A / Melatonin Receptor 1a Antibody - MTNR1A antibody (0.3 ug/ml) staining of KELLY lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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MTNR1A / Melatonin Receptor 1a Goat anti-Human Polyclonal (aa132-144) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
MTNR1A / Melatonin Receptor 1a Antibody - Western blot analysis of Melatonin Receptor 1a expression in A549 (A); NS-1 (B); PC12 (C) whole cell lysates.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal (160-240 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of recombinant MTNR1A / Melatonin Receptor 1a.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Bovine Monoclonal (aa216-257) Antibody
Bovine, Cow
ICC, IP, WB
Unconjugated
100 µl/$334; 200 µl/$387; 500 µl/$563; 1 ml/$678
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of recombinant MTNR1A / Melatonin Receptor 1a.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Bovine Monoclonal (aa216-257) (HRP) Antibody
Bovine, Cow
ICC, IP, WB
HRP Conjugated
100 µl/$371; 200 µl/$439; 500 µl/$705; 1 ml/$864
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of recombinant MTNR1A / Melatonin Receptor 1a.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Bovine Monoclonal (aa216-257) (Biotin) Antibody
Bovine, Cow
ICC, IP, WB
Biotin Conjugated
100 µl/$346; 200 µl/$404; 500 µl/$598; 1 ml/$746
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of recombinant MTNR1A / Melatonin Receptor 1a.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Bovine Monoclonal (aa216-257) (FITC) Antibody
Bovine, Cow
ICC, IP, WB
FITC Conjugated
100 µl/$383; 200 µl/$457; 500 µl/$758; 1 ml/$915
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of recombinant MTNR1A / Melatonin Receptor 1a.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Bovine Monoclonal (aa216-257) (APC) Antibody
Bovine, Cow
ICC, IP, WB
APC Conjugated
100 µl/$457; 200 µl/$563; 500 µl/$1,013; 1 ml/$1,190
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of recombinant MTNR1A / Melatonin Receptor 1a.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Bovine Monoclonal (aa216-257) (APC, Cy7) Antibody
Bovine, Cow
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$580; 200 µl/$811; 500 µl/$1,409; 1 ml/$1,761
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of recombinant MTNR1A / Melatonin Receptor 1a.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Bovine Monoclonal (aa216-257) (PE) Antibody
Bovine, Cow
ICC, IP, WB
PE Conjugated
100 µl/$457; 200 µl/$563; 500 µl/$1,013; 1 ml/$1,190
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of recombinant MTNR1A / Melatonin Receptor 1a.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Bovine Monoclonal (aa216-257) (Cy3) Antibody
Bovine, Cow
ICC, IP, WB
Cy3 Conjugated
100 µl/$457; 200 µl/$563; 500 µl/$1,013; 1 ml/$1,190
MTNR1A / Melatonin Receptor 1a Antibody - Immunofluorescence analysis of HepG2 cells, using MTR1A Antibody. The picture on the right is blocked with the synthesized peptide.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal (aa191-240) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
MTNR1A / Melatonin Receptor 1a Antibody - Western Blot;Sample: Recombinant MTNR1A, Human.
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MTNR1A / Melatonin Receptor 1a Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581; 2 ml/$798; 5 ml/$1,296
MTNR1A / Melatonin Receptor 1a Antibody - Western blot of MTNR1A antibody at 1:500 dilution. Lane 1: A549 whole cell lysate. Lane 2: sp2/0 whole cell lysate. Lane 3: PC12 whole cell lysate.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
MTNR1A / Melatonin Receptor 1a Antibody - MTNR1A antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTNR1A / Melatonin Receptor 1a Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).