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MTMR7 is a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5.
Gene Name: | myotubularin related protein 7 |
Family/Subfamily: | Protein Phosphatase , Myotubularin-Related |
Synonyms: | MTMR7, Myotubularin-related protein 7, Myotubularin related protein 7 |
Target Sequences: | AF073482 AAC77820.1 Q9Y216 |
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