Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

MTIF2

mitochondrial translational initiation factor 2

During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: mitochondrial translational initiation factor 2
Synonyms: MTIF2, IF-2(Mt), IF-2mt, IF2(mt)
Target Sequences: NM_002453 NP_002444.2 P46199

Publications (2)

1
Fidelity of translation initiation is required for coordinated respiratory complex assembly. Rudler DL, Hughes LA, Perks KL, Richman TR, Kuznetsova I, Ermer JA, Abudulai LN, Shearwood AJ, Viola HM, Hool LC, Siira SJ, Rackham O, Filipovska A. Science advances. 2019 December;5: [Full Text Article] [PubMed:31903419] [PMC:PMC6924987]
2
Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation. Nicola Ferreira, Kara L Perks, Giulia Rossetti, Danielle L Rudler, Laetitia A Hughes, Judith A Ermer, Louis H Scott, Irina Kuznetsova, Tara R Richman, Vinod K Narayana, Laila N Abudulai, Anne-Marie J Shearwood, Henrietta Cserne Szappanos, Dedreia Tull, George C Yeoh, Livia C Hool, Aleksandra Filipovska, Oliver Rackham. The EMBO journal. 2019 December;38:e102155. [Full Text Article] [PubMed:31721250] [PMC:PMC6912024]

☰ Filters
Products
Proteins (5)
Over-Expression Lysate (4)
Recombinant (1)
MTIF2 (5)
No (5)
Myc-DDK (Flag) (4)
Human (2)
Rat (1)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Purified (1)
MTIF2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
81.34 kDa
20 µg/$215
MTIF2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
81.34 kDa
20 µg/$215
MTIF2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
81.34 kDa
100 µg/$710
MTIF2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
81.34 kDa
100 µg/$710
MTIF2 Protein - Recombinant Mitochondrial Translational Initiation Factor 2 (MTIF2) by SDS-PAGE
Select
E. coli
None
53.1kDa
10 µg/$273; 50 µg/$392; 200 µg/$782; 100 µg/$625; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
Viewing 1-5 of 5 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).