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MTHFD2

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

MTHFD2 encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

Gene Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Synonyms: MTHFD2, NMDMC
Target Sequences: NM_006636 NP_006627.2 P13995

☰ Filters
Antibodies (27)
Proteins (8)
Over-Expression Lysate (4)
Primary (27)
Recombinant (4)
MTHFD2 (35)
Human (27)
Mouse (14)
Rat (11)
Bat (12)
Bovine (6)
Chicken (3)
Chimpanzee (9)
Dog (12)
Gibbon (12)
Guinea pig (12)
Hamster (9)
Horse (9)
Monkey (9)
Pig (6)
Rabbit (12)
Zebrafish (3)
IHC (7)
IHC-P (4)
WB (23)
ELISA (6)
IF (2)
Peptide-ELISA (1)
rabbit (25)
mouse (2)
Product Group
IHCPlus (1)
IgG (20)
IgG1,k (1)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (25)
1985CT220.118.31 (1)
4G7-2G3 (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
Unconjugated (15)
aa133-182 (4)
aa180-229 (4)
aa36-85 (4)
aa72-121 (4)
C-Terminus (1)
No (35)
6His-SUMO, N-terminus (1)
GST (1)
His (1)
Myc-DDK (Flag) (5)
Cow (1)
Human (5)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
MTHFD2 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100
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MTHFD2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
MTHFD2 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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MTHFD2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
MTHFD2 Antibody - 1:100 staining human lymph carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MTHFD2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MTHFD2 Antibody - Immunohistochemistry of paraffin-embedded Human mammary cancer using MTHFD2 Polyclonal Antibody at dilution of 1:100 (40x lens).
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MTHFD2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MTHFD2 Protein - Purified recombinant protein MTHFD2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
34.7 kDa
20 µg/$1,107
MTHFD2 Protein - 12.5% SDS-PAGE of human MTHFD2 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.93 kDa
10 µg/$479; 25 µg/$670
MTHFD2 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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MTHFD2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
MTHFD2 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
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MTHFD2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
MTHFD2 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using MTHFD2 Polyclonal Antibody at dilution of 1:65(×200)
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MTHFD2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MTHFD2 Antibody - All lanes: Anti-MTHFD2 Antibody (C-term) at 1:4000 dilution Lane 1: Hela whole cell lysate Lane 2: 293 whole cell lysate Lane 3: MOLT-4 whole cell lysate Lane 4: Mouse heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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MTHFD2 Mouse anti-Human Monoclonal (C-Terminus) (1985CT220.118.31) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$393
MTHFD2 Antibody - MTHFD2 monoclonal antibody (M01), clone 4G7-2G3 Western blot of MTHFD2 expression in HepG2.
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MTHFD2 Mouse anti-Human Monoclonal (4G7-2G3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
MTHFD2 Antibody - 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
WB
Unconjugated
100 µl/$424
MTHFD2 Antibody - 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Horse, Bat, Gibbon, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
MTHFD2 Antibody - HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa133-182) Antibody
Human
WB
Unconjugated
100 µl/$397
MTHFD2 Antibody - HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa133-182) (HRP) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$442
MTHFD2 Antibody - HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa133-182) (Biotin) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$442
MTHFD2 Antibody - HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa133-182) (FITC) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$442
MTHFD2 Antibody - MTHFD2 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa180-229) Antibody
Human
WB
Unconjugated
100 µl/$424
MTHFD2 Antibody - MTHFD2 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa180-229) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
MTHFD2 Antibody - MTHFD2 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTHFD2 Rabbit anti-Human Polyclonal (aa180-229) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
MTHFD2 Antibody - MTHFD2 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MTHFD2 Rabbit anti-Human Polyclonal (aa180-229) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
MTHFD2 Antibody - MTHFD2 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MTHFD2 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
WB
Unconjugated
100 µl/$424
MTHFD2 Antibody
Select
MTHFD2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
MTHFD2 Antibody - Immunochemical staining of human MTHFD2 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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MTHFD2 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
Viewing 1-25 of 35 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).