Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Gene Name: | MRG/MORF4L binding protein |
Synonyms: | MRGBP, C20orf20, Eaf7, MRG/MORF4L binding protein, MRG15BP, URCC4 |
Target Sequences: | NM_018270 NP_060740.1 Q9NV56 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.