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MRAS is a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: | muscle RAS oncogene homolog |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , RAS oncogene |
Synonyms: | MRAS, M-RAs, Ras-related protein M-Ras, Ras-related protein R-Ras3, RRAS3, Muscle RAS oncogene homolog, R-RAS3, Muscle and microspikes RAS |
Target Sequences: | NM_012219 NP_036351.3 O14807 |
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