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MPHOSPH8

M-phase phosphoprotein 8

Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression.

Gene Name: M-phase phosphoprotein 8
Synonyms: MPHOSPH8, M-phase phosphoprotein 8, M-phase phosphoprotein, mpp, M-phase phosphoprotein, mpp8, HSMPP8, RP11-523H24.1, Mpp8, TWA3
Target Sequences: NM_017520 NP_059990.2 Q99549

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Products
Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
MPHOSPH8 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
MPHOSPH8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
97 kDa
20 µg/$150
MPHOSPH8 Protein - 12.5% SDS-PAGE of human MPHOSPH8 stained with Coomassie Blue
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Wheat Germ Extract
GST
54.8 kDa
10 µg/$479; 25 µg/$670
MPHOSPH8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
97 kDa
100 µg/$494
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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).