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MPG
N-methylpurine-DNA glycosylase
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
| Gene Name: | N-methylpurine-DNA glycosylase |
| Synonyms: | MPG, 3-alkyladenine DNA glycosylase, ADPG, Anpg, AAG, APNG, CRA36.1, N-methylpurine-DNA glycosylase, PIG16, PIG11, MDG |
| Target Sequences: | NM_002434 NP_002425.2 P29372 |
Publications (1)
1
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nicola P Montaldo, Diana L Bordin, Alessandro Brambilla, Marcel Rösinger, Sarah L Fordyce Martin, Karine Øian Bjørås, Stefano Bradamante, Per Arne Aas, Antonia Furrer, Lene C Olsen, Nicolas Kunath, Marit Otterlei, Pål Sætrom, Magnar Bjørås, Leona D Samson, Barbara van Loon. Nature communications. 2019 Nov;10:5460. [Full Text Article]
[PubMed:31784530]
[PMC:PMC6884549]
Related Antibodies: LS-C133325.
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Proteins
(10)
Type
Over-Expression Lysate
(2)
Recombinant
(8)
Target
MPG
(10)
Publications
No
(10)
Tag
6His, C-terminus
(1)
GST
(1)
GST, N-terminus
(1)
GST, N-terminus + His, C-terminus
(1)
His
(3)
His-T7
(1)
Myc-DDK (Flag)
(2)
Species
Human
(7)
Mouse
(1)
Rat
(1)
Source
293T Cells
(1)
E. coli
(5)
HEK 293 Cells
(1)
Wheat Germ Extract
(2)
Yeast
(1)
Purification
Purified
(2)
E. coli
6His, C-terminus
50 µg/$411; 250 µg/$985; 10 µg/$276
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Yeast
His
34.2 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Wheat Germ Extract
GST
58.6 kDa
2 µg/$439
293T Cells
Myc-DDK (Flag)
32.19 kDa
20 µg/$150
E. coli
GST, N-terminus + His, C-terminus
58.2 kDa
50 µg/$419
HEK 293 Cells
Myc-DDK (Flag)
32.19 kDa
100 µg/$494
E. coli
His
34.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$677; 200 µg/$845; 1 mg/$1,938; 500 µg/$1,485; 5 mg/$2,955; 2 mg/$2,124
E. coli
His
31.4 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
E. coli
His-T7
33.5 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
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