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Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime.
Gene Name: | molybdenum cofactor sulfurase |
Synonyms: | MOCOS, HMCS, MCS, MoCo sulfurase, Molybdenum cofactor sulfurase |
Target Sequences: | NM_017947 NP_060417.2 Q96EN8 |
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