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MNDA

myeloid cell nuclear differentiation antigen

The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.

Gene Name: myeloid cell nuclear differentiation antigen
Synonyms: MNDA, PYHIN3
Target Sequences: NM_002432 NP_002423.1 P41218

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
MNDA (7)
No (7)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
MNDA Protein
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E. coli
His
100 µg/$511; 500 µg/$1,348; 20 µg/$311
MNDA Protein - 12.5% SDS-PAGE of human MNDA stained with Coomassie Blue
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Wheat Germ Extract
GST
72.2 kDa
2 µg/$439
MNDA Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MNDA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.7 kDa
20 µg/$150
MNDA Protein - Purified recombinant protein MNDA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.7 kDa
20 µg/$1,107
MNDA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.7 kDa
100 µg/$494
MNDA Protein - Recombinant Myeloid Cell Nuclear Differentiation Antigen By SDS-PAGE
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E. coli
His-T7
28.5 kDa
50 µg/$422; 10 µg/$278; 200 µg/$842; 100 µg/$672; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).