Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
MMP8 is a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
Gene Name: | matrix metallopeptidase 8 (neutrophil collagenase) |
Family/Subfamily: | Protease , Metallopeptidase M10A |
Synonyms: | MMP8, CLG1, HNC, Matrix metalloproteinase-8, MMP-8, Neutrophil collagenase, PMNL collagenase, PMNL-CL |
Target Sequences: | NM_002424 NP_002415.1 P22894 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.