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MMP7 / Matrilysin

matrix metallopeptidase 7 (matrilysin, uterine)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene Name: matrix metallopeptidase 7 (matrilysin, uterine)
Family/Subfamily: Protease , Metallopeptidase M10A
Synonyms: MMP7, Matrilysin, Matrin, MMP-7, MPSL1, PUMP-1, Pump-1 protease, MPMM, Uterine matrilysin, Punctuated metalloproteinase 1, Matrix metalloproteinase-7, PUMP1, Uterine metalloproteinase
Target Sequences: NM_002423 NP_002414.1 P09237

Publications (1)

1
Pre-treatment With Ranibizumab Aggravates PDT Injury and Alleviates Inflammatory Response in Choroid-Retinal Endothelial Cells. Yang Liu, Min Zhu, Ruowen Gong, Xin Wang, Lei Li, Gezhi Xu. Frontiers in cell and developmental biology. 2020 August;8:608. [Full Text Article] [PubMed:32733897] [PMC:PMC7363772]

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Proteins (12)
Over-Expression Lysate (2)
Recombinant (10)
MMP7 / Matrilysin (12)
No (12)
6His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His (3)
His, N-terminus (1)
His-T7 (2)
Myc-DDK (Flag) (2)
Human (7)
Mouse (1)
Rat (3)
293T Cells (1)
E. coli (7)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (2)
Low endotoxin level (1)
MMP7 / Matrilysin Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
MMP7 / Matrilysin Protein
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E. coli
His, N-terminus
33.5 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
MMP7 / Matrilysin Protein - Recombinant Matrix Metalloproteinase 7 By SDS-PAGE
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E. coli
His-T7
33.4 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
MMP7 / Matrilysin Protein - 12.5% SDS-PAGE of human MMP7 stained with Coomassie Blue
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Wheat Germ Extract
GST
56.1 kDa
10 µg/$479; 25 µg/$670
MMP7 / Matrilysin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MMP7 / Matrilysin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
29.66 kDa
20 µg/$150
MMP7 / Matrilysin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
29.66 kDa
100 µg/$494
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E. coli
172 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
19.03 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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E. coli
GST
46.3 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
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Yeast
His
20.9 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
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E. coli
6His, N-terminus
28 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
MMP7 / Matrilysin Protein - Recombinant Matrix Metalloproteinase 7 By SDS-PAGE
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E. coli
His-T7
33.6 kDa
10 µg/$288; 50 µg/$485; 100 µg/$775; 200 µg/$970; 1 mg/$2,104; 500 µg/$1,632; 5 mg/$3,389; 2 mg/$2,294
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).