MMP24

matrix metallopeptidase 24 (membrane-inserted)

Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin.

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Proteins (2)

Type

Recombinant (2)

Target

MMP24 (2)

Publications

No (2)

Tag

10His, N-terminus + Myc, C-terminus (1)

His-T7 (1)

Species

Human (1)

Mouse (1)

Source

E. coli (2)

Purification

Purified (1)

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Human MMP24 Protein (Recombinant His-T7) (aa429-642) - LS-G14428

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.8 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Mouse MMP24 Protein (Recombinant 10His, N-terminus + Myc, C-terminus) - LS-G136534

Source:

E. coli

Tag:

10His, N-terminus + Myc, C-terminus

Molecular Weight:

66.4 kDa

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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