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Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
Gene Name: | matrix metallopeptidase 19 |
Family/Subfamily: | Protease , Metallopeptidase M10A |
Synonyms: | MMP19, Matrix metalloproteinase 19, Matrix metalloproteinase RASI, MMP-19, MMP-18, RASI, Matrix metallopeptidase 19, Matrix metalloproteinase-18, RASI-1, Matrix metalloproteinase 18, Matrix metalloproteinase-19, MMP18 |
Target Sequences: | NM_002429 NP_002420.1 Q99542 |
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