MMP13

matrix metallopeptidase 13 (collagenase 3)

Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

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Products

Proteins (17)

Type

Over-Expression Lysate (2)

Recombinant (15)

Target

MMP13 (17)

Publications

No (17)

Tag

6His-SUMO, N-terminus (1)

GST, N-terminus (1)

His (7)

His, N-Terminal (3)

His, N-terminus (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Dog (1)

Human (6)

Mouse (2)

Pig (1)

Rabbit (2)

Rat (4)

Source

293F Cells (2)

293T Cells (1)

E. coli (12)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (4)

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Rat MMP13 Protein (Recombinant His, N-terminus) (aa62-217) - LS-G11549

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

19.1 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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Mouse MMP13 Protein (Recombinant His, N-Terminal) (aa286-462) - LS-G11550

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22.2 kDa

Price:

10 µg/$286; 50 µg/$472; 200 µg/$942; 1 mg/$2,069; 5 mg/$3,291; 2 mg/$2,257

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Human MMP13 Protein (Recombinant His) (aa103-290) - LS-G11547

Source:

E. coli

Tag:

His

Molecular Weight:

22.6 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human MMP13 Protein (Recombinant His-SUMO) (aa104-471) - LS-G20969

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

58.3 kD

Price:

100 µg/$420; 1 mg/$1,355; 20 µg/$323

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Mouse MMP13 Protein (Recombinant His) (aa66-238) - LS-G11546

Source:

E. coli

Tag:

His

Molecular Weight:

21.0 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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Human MMP13 Protein (Recombinant GST, N-terminus) (aa362-471) - LS-G59263

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MMP13 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75266

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.82 kDa

Price:

20 µg/$150

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MMP13 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99753

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.82 kDa

Price:

100 µg/$494

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Rat MMP13 Protein (Recombinant His, N-Terminal) (Leu14-Cys466) - LS-G132907

Source:

293F Cells

Tag:

His, N-Terminal

Molecular Weight:

60kDa

Price:

10 µg/$288; 50 µg/$487; 200 µg/$972; 100 µg/$780; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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Rat MMP13 Protein (Recombinant His, N-Terminal) - LS-G132821

Source:

293F Cells

Tag:

His, N-Terminal

Molecular Weight:

60kDa

Price:

10 µg/$382; 50 µg/$952; 200 µg/$1,612; 100 µg/$1,378; 1 mg/$3,041; 500 µg/$2,437; 5 mg/$6,651; 2 mg/$3,548

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Pig MMP13 Protein (Recombinant His-T7) (aa123-270) - LS-G23911

Source:

E. coli

Tag:

His-T7

Molecular Weight:

20.1 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Dog MMP13 Protein (Recombinant 6His-SUMO, N-terminus) (aa28-478) - LS-G56628

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human MMP13 Protein (Recombinant His) - LS-G2767

Source:

E. coli

Tag:

His

Price:

100 µg/$739; 50 µg/$523; 500 µg/$1,917; 10 µg/$292; 20 µg/$361; 250 µg/$1,285

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Human MMP13 Protein (Recombinant His) (aa290-468) - LS-G11545

Source:

E. coli

Tag:

His

Molecular Weight:

22.6 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Rat MMP13 Protein (Recombinant His) (aa280-455) - LS-G11548

Source:

E. coli

Tag:

His

Molecular Weight:

22.0 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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Rabbit MMP13 Protein (Recombinant His) (aa70-245) - LS-G11551

Source:

E. coli

Tag:

His

Molecular Weight:

20.9 kDa

Price:

10 µg/$293; 50 µg/$517; 100 µg/$827; 200 µg/$1,026; 1 mg/$2,182; 500 µg/$1,702; 5 mg/$3,613; 2 mg/$2,373

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Rabbit MMP13 Protein (Recombinant His) (aa287-449) - LS-G11559

Source:

E. coli

Tag:

His

Molecular Weight:

20.3 kDa

Price:

10 µg/$293; 50 µg/$517; 100 µg/$827; 200 µg/$1,026; 1 mg/$2,182; 500 µg/$1,702; 5 mg/$3,613; 2 mg/$2,373

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