MMP13

matrix metallopeptidase 13 (collagenase 3)

Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

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Antibodies (149)

ELISA Kits (46)

Proteins (17)

Type

Cell-Based (1)

Competitive EIA (2)

Custom (1)

Over-Expression Lysate (2)

Primary (149)

Recombinant (15)

Sandwich (31)

Sandwich CLIA (11)

Target

MMP13 (212)

Reactivity

Human (108)

Mouse (46)

Rat (43)

Bovine (5)

Chicken (3)

Chimpanzee (3)

Gibbon (3)

Guinea pig (4)

Horse (6)

Monkey (6)

Pig (13)

Porcine (1)

Rabbit (17)

Sheep (1)

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Application

IHC (51)

IHC-P (22)

WB (141)

ELISA (26)

ICC (2)

IF (37)

IP (2)

Peptide-ELISA (3)

RNAi (1)

Host

rabbit (114)

mouse (27)

guinea pig (8)

Product Group

IHCPlus (4)

Isotype

IgG (45)

IgG1 (8)

IgG1,k (1)

IgG2a (16)

IgG2a,k (1)

Clonality

monoclonal mc (26)

polyclonal pc (123)

Clone

3B11 (1)

OTI1F1 (2)

OTI1G5 (2)

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OTI2D11 (2)

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OTI2F4 (2)

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OTI3G1 (2)

OTI3H3 (2)

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Format

12 x 8-Well Microstrips (3)

96-Well Microplate (7)

96-Well Strip Plate (36)

APC (8)

APC Conjugated (11)

Azide-free (2)

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Carrier-free (12)

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Cy7 Conjugated (8)

FITC Conjugated (14)

HRP Conjugated (14)

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Preservative Free (1)

Unconjugated (69)

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Epitope

aa104-471 (24)

aa103-290 (8)

aa280-455 (8)

aa286-462 (8)

aa290-468 (8)

aa62-217 (8)

aa66-238 (8)

aa70-245 (8)

aa123-270 (7)

aa253-282 (7)

aa295-324 (7)

aa251-300 (3)

C-Terminus (2)

N-Terminus (2)

10-90 aa, N-terminal (1)

Internal (1)

Leu22 (1)

aa10-59 (1)

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No (209)

Yes (3)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (7)

Cell Lysates (5)

Cell Supernatant (1)

Plasma (41)

Serum (41)

Tissue Homogenates (13)

Tag

6His-SUMO, N-terminus (1)

GST, N-terminus (1)

His (7)

His, N-Terminal (3)

His, N-terminus (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Dog (1)

Human (6)

Mouse (2)

Pig (1)

Rabbit (2)

Rat (4)

Source

293F Cells (2)

293T Cells (1)

E. coli (12)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (4)

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IHC-plus™ MMP13 Antibody (Internal) LS-A1553

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(4.0) Rating

Antibody:

MMP13 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Rabbit, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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IHC-plus™ MMP13 Antibody (C-Terminus) LS-A1555

Fast Shipping

(4.0) Rating

Antibody:

MMP13 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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IHC-plus™ MMP13 Antibody (N-Terminus) LS-A1552

Fast Shipping

(4.0) Rating

Antibody:

MMP13 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ MMP13 Antibody (C-Terminus) LS-A1554

Fast Shipping

(4.0) Rating

Antibody:

MMP13 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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MMP13 Antibody (N-Terminus) LS-C352547

Antibody:

MMP13 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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Mouse MMP13 (Sandwich ELISA) ELISA Kit - LS-F5519

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$782

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Rabbit MMP13 (Sandwich ELISA) ELISA Kit - LS-F5900

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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Rat MMP13 (Sandwich ELISA) ELISA Kit - LS-F13323

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

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Rabbit MMP13 (Sandwich ELISA) ELISA Kit - LS-F21889

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rabbit

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Rat MMP13 Protein (Recombinant His, N-terminus) (aa62-217) - LS-G11549

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

19.1 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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Mouse MMP13 Protein (Recombinant His, N-Terminal) (aa286-462) - LS-G11550

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22.2 kDa

Price:

10 µg/$286; 50 µg/$472; 200 µg/$942; 1 mg/$2,069; 5 mg/$3,291; 2 mg/$2,257

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MMP13 Antibody (aa253-282) LS-C323043

Antibody:

MMP13 Rabbit anti-Human Polyclonal (aa253-282) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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Mouse MMP13 (Sandwich ELISA) ELISA Kit - LS-F12053

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

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Human MMP13 (CLIA) ELISA Kit - LS-F26160

(4.0) Rating

(1) Publication(s)

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

54.9 - 40000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$851

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MMP13 Antibody (aa66-238) LS-C295311

Antibody:

MMP13 Rabbit anti-Mouse Polyclonal (aa66-238) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

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MMP13 Antibody LS-C666807

Antibody:

MMP13 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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Human MMP13 (Sandwich ELISA) ELISA Kit - LS-F156

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

8.23 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

Select

Rat MMP13 (Sandwich ELISA) ELISA Kit - LS-F5518

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

Select

Rat MMP13 (Sandwich ELISA) ELISA Kit - LS-F32435

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse MMP13 (Sandwich ELISA) ELISA Kit - LS-F24025

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human MMP13 (Sandwich ELISA) ELISA Kit - LS-F24618

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$582

Select

Human MMP13 Protein (Recombinant His) (aa103-290) - LS-G11547

Source:

E. coli

Tag:

His

Molecular Weight:

22.6 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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MMP13 Antibody (aa104-471, clone OTI2D11) LS-C338162

Antibody:

MMP13 Mouse anti-Human Monoclonal (aa104-471) (OTI2D11) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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MMP13 Antibody LS-C318143

Antibody:

MMP13 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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MMP13 Antibody LS-C285778

Antibody:

MMP13 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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