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MMP10

matrix metallopeptidase 10 (stromelysin 2)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene Name: matrix metallopeptidase 10 (stromelysin 2)
Family/Subfamily: Protease , Metallopeptidase M10A
Synonyms: MMP10, Matrix metalloproteinase-10, SL-2, STMY2, Stromelysin 2, Stromelysin-2, MMP-10, Transin 2, Transin-2, Stromelysin2, Matrix metalloprotease 10
Target Sequences: NM_002425 NP_002416.1 P09238

Publications (2)

1
Type-specific dysregulation of matrix metalloproteinases and their tissue inhibitors in end-stage heart failure patients: relationship between MMP-10 and LV remodelling. Wei Y, Cui C, Lainscak M, Zhang X, Li J, Huang J, Zhang H, Zheng Z, Hu S. Journal of cellular and molecular medicine. 2011 15:773-82. (ICC, WB; Rat) [PubMed:20219015]
2
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article] [PubMed:31771627] [PMC:PMC6878650] Related Antibodies: LS-C118518.

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Products
Antibodies (80)
Primary (80)
MMP10 (80)
Human (64)
Mouse (29)
Rat (16)
IHC (21)
IHC-P (5)
WB (74)
Flo (1)
ELISA (21)
ICC (1)
IF (7)
IP (9)
Peptide-ELISA (3)
rabbit (69)
mouse (11)
IgG (35)
IgG1 (4)
IgG2b (6)
monoclonal mc (10)
polyclonal pc (70)
APC (3)
APC Conjugated (6)
Azide-free (1)
Biotin Conjugated (11)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (8)
HRP Conjugated (8)
Magnetic beads Conjugated (1)
PE Conjugated (6)
Preservative Free (4)
Sepharose Conjugated (1)
Unconjugated (33)
aa154-465 (8)
aa154-472 (8)
aa99-476 (8)
aa394-423 (7)
N-Terminus (4)
aa410-422 (4)
330-410 aa, C-terminal (1)
50-130 aa, Internal (1)
C-Terminus (1)
Cleaved-Phe99 (1)
Ile387 (1)
Internal (1)
aa361-410 (1)
aa409-443 (1)
aa80-129 (1)
No (79)
Yes (1)
MMP10 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using MMP-10 Antibody. The picture on the right is blocked with the synthesized peptide.
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MMP10 Rabbit anti-Human Polyclonal (aa361-410) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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MMP10 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
MMP10 Antibody - Immunodetection Analysis: Representative blot from a previous lot. Lane 1, recombinant protein MMP10. The membrane blot was probed with antiMMP10 primary antibody (0.2 µg/ml). Proteins were visualized using a Donkey anti-rabbit secondary antibody conjugated to IRDye 800CW detection system. Arrows indicate recombinant protein MMP10 from E.coli cell (55kDa).
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MMP10 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
MMP10 Antibody - Immunohistochemical analysis of MMP10 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MMP10 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
MMP10 Antibody - Western blot of MMP10 antibody.
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MMP10 Rabbit anti-Mouse Polyclonal (aa154-472) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
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MMP10 Rabbit anti-Human Polyclonal (aa394-423) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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MMP10 Rabbit anti-Human Polyclonal (aa394-423) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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MMP10 Rabbit anti-Human Polyclonal (aa394-423) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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MMP10 Rabbit anti-Human Polyclonal (aa394-423) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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MMP10 Rabbit anti-Human Polyclonal (aa394-423) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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MMP10 Rabbit anti-Human Polyclonal (aa394-423) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
MMP10 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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MMP10 Rabbit anti-Human Polyclonal (aa394-423) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
MMP10 Antibody - Immunohistochemistry - Anti-MMP10 Picoband Antibody
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MMP10 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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MMP10 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
500 µl/$884
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MMP10 Rabbit anti-Human Polyclonal (330-410 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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MMP10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100 µl/$391
MMP10 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using MMP10 Antibody at dilution of 1:50
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MMP10 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
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MMP10 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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MMP10 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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MMP10 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
MMP10 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using MMP-10 antibody.
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MMP10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
MMP10 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600 was used as secondary antibody.
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MMP10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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MMP10 Rabbit anti-Human Polyclonal (Ile387) Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
50 µl/$321; 100 µl/$403
MMP10 Antibody - Immunohistochemistry of paraffin-embedded rat kidney tissue.
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MMP10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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MMP10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).