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Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond.
Gene Name: | membrane metallo-endopeptidase-like 1 |
Family/Subfamily: | Protease , Metallopeptidase Other |
Synonyms: | MMEL1, MELL1, MMEL2, NEP2, NEPII, Neprilysin-2, NL2, NEP2(m), Neprilysin II, Neprilysin-like 2, NL1, SEP, Soluble secreted endopeptidase, Zinc metallopeptidase |
Target Sequences: | NM_033467 NP_258428.2 Q495T6 |
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