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MLYCD / MCD

Malonyl-CoA Decarboxylase

Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling. May play a role in controlling the extent of ischemic injury by promoting glucose oxidation.

Gene Name: Malonyl-CoA Decarboxylase
Synonyms: MLYCD, MCD, HMCD, Malonyl-CoA decarboxylase
Target Sequences: NM_012213 NP_036345.2 O95822

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
MLYCD / MCD (6)
No (6)
10His, N-terminus + Myc, C-terminus (1)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
MLYCD / MCD Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
54.8 kDa
20 µg/$150
MLYCD / MCD Protein - 12.5% SDS-PAGE of human MLYCD stained with Coomassie Blue
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Wheat Germ Extract
GST
81.4 kDa
10 µg/$479; 25 µg/$670
MLYCD / MCD Protein - Recombinant Malonyl Coenzyme A Decarboxylase By SDS-PAGE
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E. coli
His-T7
37.8 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
MLYCD / MCD Protein - Purified recombinant protein MLYCD was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
54.8 kDa
20 µg/$1,107
MLYCD / MCD Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
1 mg/$1,486; 100 µg/$451; 20 µg/$339
MLYCD / MCD Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
54.8 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).